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The oral median lethal dose in mice was 353 mg kg estimated clarinex reditabs exposures were approximately 290 times the human daily oral dose on a mg m 2 basis .

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In multidose clinical safety studies, where metabolizer status was identified, a total of 94 poor metabolizers and 123 normal metabolizers were enrolled and treated with clarinex oral solution for 15-35 days.

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In two double-blind, placebo-controlled, randomized clinical trials of six weeks duration, at the pre-specified one-week primary time point evaluation, clarinex reditabs tablets significantly reduced the severity of pruritus when compared to placebo table 5 .

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Another issue associated with vioxx, an anti-inflammatory drug that the bioallers animal clarinex is for many a small bulb where clarinex is not a cure is because they didn t mention evaluation of irritants that aren t true allergens.

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however, no specific interactions with clarinex are known at this time.

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